Biohacking dentistry. Generation four.

The dentist your doctor calls when nothing else has worked.

Biological dentistry, since before it had a name.

Dr. Alireza Panahpour, DDS · Santa Monica & Sacramento · By referral, since 1994

Portrait of Dr. Alireza Panahpour, DDS
Patients arrive from fourteen countries

The thesis.

The mouth is the upstream
of half your biomarkers.

You've optimised sleep, glucose, HRV, training, and stress. The mouth is the leverage point most have never tested. Chronic oral inflammation drives systemic CRP. Bite alignment shapes sleep quality. Mercury inhibits mitochondria. This is the next protocol in the stack.

Because you are a physical structure inside an energetic body — and every burden in the mouth is felt somewhere else.

The doctor · Dr. Alireza Panahpour, DDS

Practiced quietly, for thirty years.

I · 1976 01 / 03

First chair at ten.

Fourth-generation practitioner. Sat in his father's chair at ten years old. Learned the architecture of teeth before he had words for most other things in the world — what survives, what fails, what the body will accept.

4 GEN.Of dentists in the family AGE 10At his father's practice

Trained where the field is rewritten.

UCLA and Cal State Northridge in parallel for pre-medical studies. Accepted to dental school before the degree was finished. DDS from the University of the Pacific, Dugoni. Postgraduate at NYU. A Master's in electro-acupuncture — cardiothoracic program — at Columbia. The Alleman-Deliperi Center for Biomimetic Dentistry in Sardinia. Implantology in Sweden — the year Sweden banned mercury. Most recently, a Master's in aesthetic medicine from Queen Mary University of London.

UCLA · CSUNPre-medical studies DDSPacific · Dugoni NYUPostgraduate COLUMBIAM.Sc. Electro-acupuncture SARDINIABiomimetic SWEDENImplantology QUEEN MARYM.Sc. Aesthetic Medicine

In practice — quietly — since 1994.

Certified Instructor of Biomimetic Dentistry. Author of The Good Dentist (2016). Former Dental Director at South Coast Medical Center for New Medicine and La Luz Wellness Center in Mexico. His continuing-education pace runs about 2.5× the profession's requirement — every year, for thirty years.

1994In biological practice PATENTCasanova Facelift™ 2020 NYPDForensic dentistry · 1999–01 70%Physician-referred 14+Countries 150 / YRCE units IAOMTMember IABDMMember HDAMember ABDMember AOTMember IADRMember

Six standing protocols.

Heritage tools. Cutting-edge practice.

A short index of the standing procedures. Each engineered to remove a specific systemic burden — and to leave the body more capable than it was before the chair.

P · 01 Structural Alignment

The first cause of failure isn't decay. It's the bite.

An unbalanced bite radiates from the jaw through the skull, into the neck, down to the adrenals and sleep. Diagnose the chain. Realign it. The body recovers.

Tap each anchor on the anatomy to trace the chain.

0×

higher risk of implant failure in bruxers.source ↗

Bruxism roughly doubles the risk of implant loss. Material choice matters. Bite matters more.

Before & after · scroll to reveal

Rebalance the bite.
The body follows.

Same patient. Same pose. Three months of bite therapy between the two frames. Head-and-face detail obscured for privacy — every case is published with written authorization on file.

P · 02 Zirconia Implantology

Ceramic, not metal. Inert, not magnetic.

Yttria-stabilised zirconia. No galvanic interference, no chronic metal load. The biocompatible standard for patients whose body knows the difference. Drag to compare the bone interface, vascularity, and biological response.

Drag to compare

Titanium · Metal Zirconia · Ceramic

Titanium · the conventional standard

Material
Ti-6Al-4V alloy
Electrical
Conductive · galvanic with adjacent metals
Bio-response
Foreign-body capsule · low-grade inflammation
Aesthetic
Grey shadow at gumline over time

Zirconia · in practice since 2001

Material
Yttria-stabilised ZrO₂
Electrical
Inert · no galvanic interference
Bio-response
Bone integrates · no chronic immune signal
Aesthetic
White · invisible under tissue

P · 03 Safe Mercury Removal

Remove the load. Without releasing it.

Mercury vapor releases under heat and drilling. A standard removal makes the patient breathe what you were trying to take out. The SMART protocol is engineered so the load comes out and stays out.

SMART The five-stage extraction IAOMT-certified
  1. 01 Isolation. Rubber dam seals the tooth from the rest of the mouth.
  2. 02 Capture. High-volume evacuation pulls vapor and particulate at the source.
  3. 03 Oxygen. Supplemental O₂ via nasal cannula, away from the field.
  4. 04 PPE. Full protection for patient and operator — vapor mask, face shield, gowns.
  5. 05 Section & chunk. Amalgam removed in cooled solid pieces, never ground into dust.

0%

urinary mercury · 12 months post-removal.source ↗

Published follow-up studies show geometric-mean urinary mercury falls back to amalgam-free baseline within a year of complete removal — with a two-month half-life the drop begins fast (Begerow 1994; Sandborgh-Englund 1998).

P · 04 Cavitation Surgery

The infection your x-ray missed.

When old extractions don't heal properly — wisdom teeth, failed root canals — a hidden cavity of soft tissue and biofilm remains in the jaw. Cone-beam CT finds it. Ozone and PRF clear it. A chronic, perpetual immune burden, finally lifted.

PROCEDURE The five-stage exposure 3D-Imaging guided
  1. 01Imaging. Cone-beam CT finds what panoramic x-rays cannot see.
  2. 02Access. Minimal-invasive surgical entry to the hidden cavity.
  3. 03Debridement & laser. Physically clear necrotic tissue and biofilm, then laser-disinfect the bone.
  4. 04Ozone wash. Medical-grade O₃ at high concentration sterilizes the field.
  5. 05PRF graft. Your own platelet-rich fibrin seals and rebuilds the bone.

0%

reduction in systemic CRP · six months post oral-infection treatment.source ↗

Inflammation markers measured pre- and post-procedure across the practice's chronic-fatigue cohort.

P · 05 Ozone Therapy

The field, cleared. Before anything closes.

Medical-grade ozone is the adjunct in every surgical and restorative procedure where the goal is to leave the tissue more capable than it was before. Sterilizes without antibiotics. Accelerates healing. Used by Dr. Panahpour since 2008.

APPLICATION Four standing protocols AAO-certified
  1. 01Insufflation. Gaseous O₃ delivered directly into surgical sites and cavities.
  2. 02Ozonated water. Irrigation of periodontal pockets and root canals.
  3. 03Ozonated oil. Slow-release antimicrobial for post-operative healing.
  4. 04Activation. Adjunct to every restorative procedure — before bonding, before closing.

0%+

reduction of oral pathogenic biofilm — within 60 seconds.source ↗

Ozone reduces S. mutans, E. faecalis, and C. albicans biofilm by more than 99% within 60 seconds — with significantly lower cytotoxicity to human gingival and periodontal cells than chlorhexidine or sodium hypochlorite (Huth 2006; 2009).

P · 06 Biomimetic Restoration

Less drilling. Longer life.

Trained at the Alleman-Deliperi school in Sardinia. Conventional restorations replace tooth structure. Biomimetic restorations restore the tooth's mechanical behavior — and very often, they replace a root canal entirely.

TECHNIQUE The four-stage rebuild Alleman-Deliperi · Sardinia
  1. 01Excavate by stiffness. Remove only decayed structure — preserve all that holds.
  2. 02Bioactive base. A resin layer that mimics dentin's flex and bonds to it.
  3. 03Enamel-dentin junction bond. The body's natural seam, restored chemically.
  4. 04Sculpt the cusps. Restore the architectural cusps that distribute load.

SAME LIFE.
MORE TOOTH.

Comparable survival to crowns — with the natural tooth preserved underneath.source ↗

Peer-reviewed systematic reviews find bonded biomimetic restorations achieve survival rates comparable to conventional PFM crowns on posterior teeth — while conserving the enamel and dentin a crown would otherwise remove. The restoration matches. The tooth outlives.

Beyond the six.

Adjacent disciplines, same standard.

The six protocols are the standing framework. These are the parallel disciplines Dr. Panahpour spent decades formalizing — trained where they are practiced best, applied only when the case calls for them, and priced without upsell.

Bite therapy

Non-surgical bite balancing.

The primary entry point for structural cases. A single appliance realigns the bite so the skull, neck, shoulders, and hips can decompress inside weeks.

Facial aesthetics

Queen Mary, University of London.

Facial aesthetic treatments applied where clinically indicated as part of a whole-face, whole-body plan — never cosmetic in isolation.

Electro-acupuncture

Columbia University.

Electro-acupuncture, cardiothoracic. A non-pharmaceutical adjunct for pain, inflammation, and post-surgical healing. Used across every protocol above.

Instructor · 5+ years

Klinghardt Academy of Neurobiology.

Trained and later taught Autonomic Response Testing, Applied Psycho-Neurobiology, and Mental Field Therapy — methods for locating hidden infections and toxins, and for treating pain that has no structural cause.

Own patent · U.S. 2020

Casanova Facelift Technology

Dr. Panahpour's patented facial-aesthetic protocol, built out of his aesthetic-medicine training. Available on its own site.

Visit casanova­facelift.com

Measurement.

30% source ↗

Reduction in systemic inflammation.

In the peer-reviewed literature, controlling chronic oral infection produces measurable drops in circulating CRP and IL-6 within months (D'Aiuto 2004). The mouth is a printer for the bloodstream. Fix the mouth, the labs move. Your numbers are your own.

SECTION 05

By the numbers.

A practice that measures the mouth-body connection in labs, in sleep data, and in the miles patients travel to sit in the chair. These are the standing facts, verified every year.

0YRS

Continuous clinical practice
in California since 1994

0%source ↗

Improvement in sleep-quality score
PSQI · bruxism cohort, 3 months of occlusal therapy

0%

Of new patients arrive by
physician referral, not marketing

0+

Countries patients travel from
to sit in this chair

In his own words.

Meet Dr. Panahpour.

Before the protocols, the citations, and the thirty years — here he is explaining the systemic model himself. Nine minutes, no script.

Tap the screen to play. The video runs right here.

Voices · Selected

Patients
and the press.
In their own words.

A decade-plus of televised interviews, patient stories, and long-form podcasts — with the credentials to back every word. Tap any frame to watch.

Scroll to move through

TV · NBC · 2014

The breast cancer & root canal connectionNBC · National broadcast

I met Dr. Panahpour when I was nearly dying — spending hours a day seizing, barely cognitive, trapped in chronic illness. Others gave me thirty minutes. He and his wife Susie sat with me for over ninety, and came back many times. Three years later, I'm healthy and well. I've since referred another patient to him because I trust no one more in this field.

A.H. · PatientAuthorization on file · 2025

Recurring guest

Biomimetic dentistry & mercury removalDr. Wendy Myers

I've had three surgeries with Dr. Panahpour and I couldn't be in better hands. His focus on the whole-body system, his constantly updated knowledge, and his genuine care for me as a patient are second to none. I would whole-heartedly recommend him to anyone who wants to understand the connection between oral health and body health.

S.B. · PatientAuthorization on file · 2024

YouTube

Cavitations & biofilmDr. Wendy Myers

The Wellness Hour

Holistic dental Santa MonicaRandy Alvarez

I feel more bright. Less fatigued. My body is very, very happy with getting rid of that.

M.K. · PatientAuthorization on file · 2025 · initials by request

Times Square · 1540 B'way

Billboard feature24-hour Times Square rotation

The dentist your doctor calls when nothing else has worked.

PowerAgent NewsLA's Top 10 Dentists · Vol 32

From the practice

Dr. Alireza Panahpour, DDSBrentwood · since 1994

On the public record.

Selected appearances.

Eleven years of public conversations, teaching engagements, and interviews. When the biological-dentistry field wanted to think out loud in public, this is where the microphone landed.

2014 The Breast Cancer & Root Canal Connection. NBC · national · Breast Cancer Awareness Month special · the interview that put the mouth-body conversation on primetime Watch 2016 The Good Dentist. A casebook for patients · co-authored with Camilla Griggers, PhD · the book that translated whole-body dentistry from clinic language into plain English Read 2017 Weston A. Price Foundation · Fall Conference. Invited speaker · dental epigenetics and the traditional-diet-to-oral-health connection · the Foundation is the movement Doc's work extends Details 2017 Featured in the Bellevue Reporter. Long-form press profile · the practice, the patients, the philosophy · placed in his hometown paper before he moved south Read 2018 Casanova Facelift Workshop. IABDM · Miami · live technique demonstration of the patented facial-aesthetic protocol he later trademarked Details 2021 Remarkable Dentists Podcast. Long-form conversation on why he left conventional dentistry — and what he found on the other side of it Listen 2022 Mold, Mercury, and Biological Dentistry. Exposing Mold Podcast · Ep 67 · 1h 8m · the two hidden burdens that surface as chronic fatigue, brain fog, and autoimmune symptoms — and what to do about them Listen 2023 Dr. Talks Summit. Panel speaker · dental-body connection track · presenting alongside functional medicine's leading voices Watch 2024 Holistic Dentistry, decoded. What the Gut · with Allison · Ep 32 · 47m · how oral bacteria seed distant infections and drive systemic inflammation Listen 2024 Biomimetic Dentistry & Safe Mercury Removal. Dr. Wendy Myers · recurring guest · long-form · a deep technical walkthrough of the SMART protocol and how biomimetic rebuilds spare the root canal Watch 2025 Hidden Infections & Chronic Illness. This Healthy Life · Ep 53 · 36m · the invisible cavitation problem — jaw infections your X-ray missed but your immune system didn't Listen

Live from the practice.

Recent · reels.

Short-form conversations, clinical showcases, and case moments — straight from Dr. Panahpour's Instagram. Hover any reel to pause the scroll.

Follow along on Instagram for new reels weekly.

The conversation, elsewhere.

What others are saying about systemic dentistry.

Podcasters, colleagues, and independent voices break down the posture-and-bite link, the nervous-system impact of dental work, and the systemic-dentistry model Dr. Panahpour has been building for thirty years. Click any card to watch the full reel on Facebook.

Guest voiceHow the bite sets the whole body — posture, jaw, and the chain downstream. Guest voiceNervous-system impact — the airway, the vagus, and modern dentistry. Health In SecondsA tiny swollen nerve can affect an entire side of your face. Health In SecondsThe brain floats in a clear fluid that cushions and protects it. PostureproWhat if your posture keeps changing because your bite keeps changing the signal to your brain?

All conversations originally posted on Dr. Panahpour's Facebook. Click any card to watch the full reel with sound.

The book.

He wrote the book on healing through dentistry.

In 2016, Dr. Panahpour published The Good Dentist — a collection of patient case stories drawn from two decades of integrative practice, written with Camilla Griggers, PhD. It remains one of the few books written for patients that frames dentistry as a discipline of whole-body medicine.

A smile is an inexpensive way to improve your looks. I believe it may just be an easy way to improve your health, too. — Dr. Alireza Panahpour, The Good Dentist

The practices.

Two locations. One standard of care.

The work is done in person — nothing about the mouth-body diagnosis is remote. Patients begin in Brentwood or Sacramento depending on geography and case, and appointments are unhurried by design. Complex protocols may split across both locations.

11980 San Vicente Blvd, Suite 801 Los Angeles, California 90049

HoursBy appointment
Near10 min · Santa Monica & Bel Air
ParkingGarage on-site
Get directions

7237 East Southgate Drive, Suite E Sacramento, California 95823

HoursBy appointment
Near15 min · SMF Airport
ParkingFree, on-site
Get directions

Consultation by referral.

Request an audience.

The first conversation is long and unhurried — typically 60 to 90 minutes, phone or in person, unbilled. New patients are accepted by physician referral, by introduction from existing patients, and by the rare direct request from those who have already done the work to find this practice. Prefer written? Send a message and it lands in Dr. Panahpour's inbox with full context intact.

Or send a message — it goes straight to Dr. Panahpour's inbox and stays on record.

Delivered to info@systemicdentist.com. Not shared, not marketed.

+1 · 310 · 986 · 6001 · info@systemicdentist.com · Santa Monica & Sacramento